• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

1-Docosanol and other long chain primary alcohols in developing rat brain.

作者信息

Natarajan V, Schmid H H

出版信息

Lipids. 1977 Jan;12(1):128-30. doi: 10.1007/BF02532985.

DOI:10.1007/BF02532985
PMID:834119
Abstract

Long chain alcohols were detected in developing rat brain at ages ranging from 5 to 40 days. They were at their highest level of 0.0109% of the total lipids at the age of 10 days and decreased to 0.0036% at the age of 40 days. They consited mainly of hexadecanol, octadecanol, octadecenol, eicosanol, docosanol, and tetracosanol. The fact that substantial amounts of fatty alcohols having more than 20 carbon atoms were present in myelinating rat brain indicated a chain length specificity in their utilization for 0'alkyl and 0'alk-1-enyl glycerolipid biosynthesis.

摘要

相似文献

1
1-Docosanol and other long chain primary alcohols in developing rat brain.
Lipids. 1977 Jan;12(1):128-30. doi: 10.1007/BF02532985.
2
Chain length specificity in the utilization of long chain alcohols for ether lipid biosynthesis in rat brain.大鼠脑中利用长链醇进行醚脂生物合成的链长特异性
Lipids. 1977 Oct;12(10):872-5. doi: 10.1007/BF02533279.
3
Metabolism of long-chain polyunsaturated alcohols in myelinating brain.大脑髓鞘形成过程中长链多不饱和醇的代谢
J Lipid Res. 1972 Jul;13(4):452-7.
4
Biosynthesis and utilization of long-chain alcohols in rat brain: aspects of chain length specificity.大鼠脑中长链醇的生物合成与利用:链长特异性方面
Arch Biochem Biophys. 1978 Apr 15;187(1):215-22. doi: 10.1016/0003-9861(78)90026-7.
5
Enhanced long-chain fatty alcohol oxidation by immobilization of alcohol dehydrogenase from S. cerevisiae.通过固定化酿酒酵母醇脱氢酶增强长链脂肪醇氧化。
Appl Microbiol Biotechnol. 2018 Jan;102(1):237-247. doi: 10.1007/s00253-017-8598-5. Epub 2017 Oct 31.
6
Manipulation of alkylglycerolipid levels in cultured cells. Fatty alcohol versus alkylglycerol supplements.
Biochim Biophys Acta. 1980 Mar 21;617(3):410-8. doi: 10.1016/0005-2760(80)90007-7.
7
On the oxidation of long-chain polyunsaturated alcohols by myelinating rat brain.
Biochem Biophys Res Commun. 1972 Jul 11;48(1):94-100. doi: 10.1016/0006-291x(72)90348-8.
8
Competing pathways in the formation of alkyl, alk-1-enyl and acyl moieties in the lipids of mammalian tissues.哺乳动物组织脂质中烷基、烯丙基和酰基部分形成过程中的竞争途径。
Eur J Biochem. 1980;107(1):289-94. doi: 10.1111/j.1432-1033.1980.tb04649.x.
9
Radioactive labelling of lipids in rat neurosarcoma by intravenous injection of [1-14C]-octadecenol.通过静脉注射[1-¹⁴C]-十八碳烯醇对大鼠神经肉瘤中的脂质进行放射性标记。
Z Naturforsch C Biosci. 1979 Sep-Oct;34(9-10):885-7. doi: 10.1515/znc-1979-9-1038.
10
Substrate specificities in ether lipid biosynthesis. Metabolism of polyunsaturated fatty acids and alcohols by rat brain microsomes.醚脂生物合成中的底物特异性。大鼠脑微粒体对多不饱和脂肪酸和醇的代谢。
Biochem Biophys Res Commun. 1977 Nov 21;79(2):411-6. doi: 10.1016/0006-291x(77)90173-5.

引用本文的文献

1
Neurotrophic Natural Products.神经营养天然产物。
Prog Chem Org Nat Prod. 2024;123:1-473. doi: 10.1007/978-3-031-42422-9_1.
2
Chain length specificity in the utilization of long chain alcohols for ether lipid biosynthesis in rat brain.大鼠脑中利用长链醇进行醚脂生物合成的链长特异性
Lipids. 1977 Oct;12(10):872-5. doi: 10.1007/BF02533279.

本文引用的文献

1
A simple method for the isolation and purification of total lipides from animal tissues.一种从动物组织中分离和纯化总脂质的简单方法。
J Biol Chem. 1957 May;226(1):497-509.
2
Detection and isolation of minor lipid constituents.微量脂质成分的检测与分离
J Lipid Res. 1967 Nov;8(6):692-3.
3
Reductive and oxidative biosynthesis of plasmalogens in myelinating brain.髓鞘形成脑内缩醛磷脂的还原与氧化生物合成
J Lipid Res. 1970 Sep;11(5):412-9.
4
Long-chain alcohols in mammalian tissues.哺乳动物组织中的长链醇。
Chem Phys Lipids. 1970 Apr;4(2):243-6. doi: 10.1016/0009-3084(70)90056-3.
5
Metabolism of sphingosine bases. XIV. Sphinganine (dihydrosphingosine), an effective donor of the alk-1-enyl chain of plasmalogens.鞘氨醇碱基的代谢。十四。二氢鞘氨醇(神经鞘氨醇),缩醛磷脂中alk-1-烯基链的有效供体。
Hoppe Seylers Z Physiol Chem. 1970 Jul;351(7):875-83. doi: 10.1515/bchm2.1970.351.2.875.
6
Formation of 1-O-2'-hydroxyalkyl glycerophosphatides from 1,2-heptadecanediol in myelinating brain.在有髓鞘形成的大脑中,由1,2-十七烷二醇形成1-O-2'-羟烷基甘油磷脂。
J Lipid Res. 1971 Nov;12(6):740-6.
7
Metabolism of long-chain polyunsaturated alcohols in myelinating brain.大脑髓鞘形成过程中长链多不饱和醇的代谢
J Lipid Res. 1972 Jul;13(4):452-7.
8
[The formation of plasmalogens at the time of myelination in the rat (author's transl)].[大鼠髓鞘形成时缩醛磷脂的形成(作者译)]
Hoppe Seylers Z Physiol Chem. 1974 May;355(5):557-63.
9
Ozonolysis of long-chain cyclic acetals: formation of monoesters.长链环状缩醛的臭氧分解:单酯的形成。
J Lipid Res. 1974 Sep;15(5):528-9.
10
Synthesis of alcohol and wax ester by a cell-free system in Mycobacterium tuberculosis.
Biochim Biophys Acta. 1972 Jan 27;260(1):41-8. doi: 10.1016/0005-2760(72)90072-0.