Rädecke J, Waninger J, Schlotterbeck E, Farthmann E H
Abteilung Allgemeine Chirurge mit Poliklinik, Chirurgische Universitätsklinik Freiburg.
Zentralbl Chir. 1993;118(6):337-41.
In a prospective study designed to assess the situation following cholecystectomy carried out at the Department of Surgery of the University of Freiburg, 105 patients were examined between August, 1988 and December, 1989. Out of 80 patients who were followed up, 64 had undergone cholecystectomy alone and the remaining 16 had been additionally subjected to exploration of the common bile duct. 80% of the patients reported that their preoperative symptoms had disappeared altogether, 8% admitted some improvement and 10% complained that their condition was unchanged. Specific questioning resulted in the reporting of persistent symptoms in 54%, and these consisted mostly of general complaints such as dyspepsia, flatulence, food intolerance and dull upper abdominal pain. These complaints were vanished or appeared with equal frequency following operation. Objective clinical findings could not be confirmed. Comparison between the pre- and postoperative signs in these patients established a statistically significant correlation (p < 0.05) between the patient's age and the severity of the preoperative symptoms on the one hand and a satisfactory postoperative outcome on the other. This also applied to patients for whom an examination of the bile duct was necessary.
在一项旨在评估弗莱堡大学外科实施胆囊切除术后情况的前瞻性研究中,1988年8月至1989年12月期间对105例患者进行了检查。在80例接受随访的患者中,64例仅接受了胆囊切除术,其余16例还接受了胆总管探查。80%的患者报告其术前症状完全消失,8%承认有一定改善,10%抱怨病情未变。进一步询问发现,54%的患者报告有持续症状,这些症状主要是消化不良、肠胃胀气、食物不耐受和上腹部隐痛等一般不适。这些不适在术后消失或出现的频率相同。客观的临床检查结果无法得到证实。对这些患者术前和术后体征的比较表明,患者年龄与术前症状严重程度之间以及与术后良好结果之间在统计学上存在显著相关性(p<0.05)。这也适用于那些需要检查胆管的患者。