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Respinomycins A1, A2 B, C and D, a novel group of anthracycline antibiotics. I. Taxonomy, fermentation, isolation and biological activities.

作者信息

Ubukata M, Osada H, Kudo T, Isono K

机构信息

Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.

出版信息

J Antibiot (Tokyo). 1993 Jun;46(6):936-41. doi: 10.7164/antibiotics.46.936.

DOI:10.7164/antibiotics.46.936
PMID:8344875
Abstract

Respinomycins are a novel group of anthracycline antibiotics produced by Streptomyces xanthocidicus. Respinomycins A1, A2, B, C and D were isolated by EtOAc extraction, silica gel column chromatography, centrifugal partition chromatography and preparative silica gel thin layer chromatography. Respinomycins A1 and A2 induced the terminal differentiation of human leukemia K-562 cells.

摘要

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