Rosenwasser A M
Department of Psychology, University of Maine, Orono 04469-5742.
Physiol Behav. 1993 Jun;53(6):1035-41. doi: 10.1016/0031-9384(93)90356-k.
This study sought to define the generality of a previous finding that the spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rat strains differ in free-running circadian period when maintained in running-wheel cages under constant light. Circadian drinking rhythms were monitored in SHRs and WKYs housed without access to running wheels under an increasing series of light intensities beginning with constant darkness. Strain differences in circadian period were seen only at relatively high light intensities, indicating that SHRs and WKYs differ in circadian light sensitivity. Since SHRs and WKYs differ in circadian period with or without access to running wheels, this strain difference is not likely to depend on differential locomotor activity levels. SHRs and WKYs also differed in spectral profile and circadian waveform, but only under low light intensities. At higher intensities, dissociation of rhythmicity was seen in both strains.
本研究旨在确定先前一项研究结果的普遍性，该结果表明，在持续光照下饲养于跑步轮笼中的自发性高血压（SHR）大鼠和血压正常的Wistar-Kyoto（WKY）大鼠品系，其自由运行的昼夜节律周期存在差异。从持续黑暗开始，在一系列不断增加的光照强度下，对饲养在无跑步轮环境中的SHR大鼠和WKY大鼠的昼夜饮水节律进行监测。仅在相对较高的光照强度下观察到昼夜节律周期的品系差异，这表明SHR大鼠和WKY大鼠在昼夜光敏感性方面存在差异。由于有无跑步轮时SHR大鼠和WKY大鼠的昼夜节律周期均存在差异，因此这种品系差异不太可能取决于不同的运动活动水平。SHR大鼠和WKY大鼠在光谱特征和昼夜波形方面也存在差异，但仅在低光照强度下如此。在较高强度下，两个品系均出现节律性解离。
