Clifton-Hadley R S, Wilesmith J W, Stuart F A
Epidemiology Department, Ministry of Agriculture, Fisheries and Food, New Haw, Addlestone, Surrey.
Epidemiol Infect. 1993 Aug;111(1):9-19. doi: 10.1017/s0950268800056624.
This study investigates the course of tuberculosis in a naturally infected badger population, its impact on the population and the risk of spread to other species in the light of capture data and post-mortem findings from 47 tuberculous badgers, stratified by age group and sex, accrued since 1975. The findings are compared with those for 260 badgers from the same population in whom no evidence of infection was detected. Detailed estimates of seasonal variations in bodyweight for uninfected male and female cub, yearling and adult badgers are presented and compared to the weights at post-mortem examination of the tuberculous badgers, in whom poor condition and weight loss were the principal presenting signs. Lesions were seen especially in the lungs and associated lymph nodes, and in the kidneys. Organisms were detected intermittently in faeces, urine, sputum and discharging bite wounds. Infected animals could survive for nearly 2 years and produce cubs successfully.
本研究依据自1975年以来收集的47只患结核病獾的捕获数据和尸检结果，按年龄组和性别进行分层，调查了自然感染獾群中结核病的病程、其对种群的影响以及传播至其他物种的风险。将这些结果与来自同一獾群的260只未检测到感染迹象的獾的结果进行比较。给出了未感染的雄性和雌性幼崽、一岁獾和成年獾体重季节性变化的详细估计值，并与患结核病獾尸检时的体重进行比较，患病獾的主要表现体征为身体状况不佳和体重减轻。病变尤其见于肺部及相关淋巴结和肾脏。在粪便、尿液、痰液和有分泌物的咬伤伤口中可间歇性检测到病原体。受感染的动物可存活近2年并成功产仔。
