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使用免疫电子显微镜来证实土拉弗朗西斯菌。

Use of immunoelectron microscopy to demonstrate Francisella tularensis.

作者信息

Geisbert T W, Jahrling P B, Ezzell J W

机构信息

Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21702-5011.

出版信息

J Clin Microbiol. 1993 Jul;31(7):1936-9. doi: 10.1128/jcm.31.7.1936-1939.1993.

DOI:10.1128/jcm.31.7.1936-1939.1993
PMID:8349780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC265665/
Abstract

Three immunoelectron microscopy (IEM) methods were employed to show laboratory-cultivated Francisella tularensis. By the IEM assays, F. tularensis was distinguished from four antigenically distinct gram-negative bacteria. IEM should be a valuable tool for confirming presumptive isolates of F. tularensis and may potentially be useful for demonstrating other medically important bacteria.

摘要

采用三种免疫电子显微镜（IEM）方法来显示实验室培养的土拉弗朗西斯菌。通过IEM检测，土拉弗朗西斯菌与四种抗原性不同的革兰氏阴性菌得以区分。IEM应是确认土拉弗朗西斯菌推定分离株的一种有价值的工具，并且可能在证明其他医学上重要的细菌方面具有潜在用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/74657142a94a/jcm00019-0276-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/84ed987c1a4a/jcm00019-0275-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/52d6c14e01cf/jcm00019-0275-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/058285bbf91a/jcm00019-0276-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/74657142a94a/jcm00019-0276-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/84ed987c1a4a/jcm00019-0275-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/52d6c14e01cf/jcm00019-0275-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/058285bbf91a/jcm00019-0276-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213d/265665/74657142a94a/jcm00019-0276-b.jpg

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本文引用的文献

1
An analysis of forty-two cases of laboratory-acquired tularemia. Treatment with broad spectrum antibiotics.42例实验室获得性兔热病分析。采用广谱抗生素治疗。
Am J Med. 1961 May;30:785-806. doi: 10.1016/0002-9343(61)90214-5.
2
Evaluation of a safranin-O-stained antigen microagglutination test for francisella tularensis antibodies.用于检测土拉弗朗西斯菌抗体的番红O染色抗原微凝集试验的评估
J Clin Microbiol. 1980 Feb;11(2):146-8. doi: 10.1128/jcm.11.2.146-148.1980.
3
Demonstration of Francisella tularensis (syn. Pasteurella tularensis) in sylvan animals with the aid of fluorescent antibodies.
Role of the wbt locus of Francisella tularensis in lipopolysaccharide O-antigen biogenesis and pathogenicity.
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Infect Immun. 2007 Jan;75(1):536-41. doi: 10.1128/IAI.01429-06. Epub 2006 Oct 9.
Acta Pathol Microbiol Scand B Microbiol Immunol. 1970;78(5):647-51. doi: 10.1111/j.1699-0463.1970.tb04351.x.
4
Agglutination and ELISA methods in the diagnosis of tularemia in different clinical forms and severities of the disease.凝集试验和酶联免疫吸附测定法在不同临床类型和疾病严重程度的兔热病诊断中的应用
J Infect Dis. 1986 Jan;153(1):142-5. doi: 10.1093/infdis/153.1.142.
5
Agglutinins and antibodies to Francisella tularensis outer membrane antigens in the early diagnosis of disease during an outbreak of tularemia.土拉菌病暴发期间，用土拉弗朗西斯菌外膜抗原凝集素和抗体进行疾病的早期诊断。
J Clin Microbiol. 1988 Mar;26(3):433-7. doi: 10.1128/jcm.26.3.433-437.1988.
6
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7
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8
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Appl Environ Microbiol. 1990 Apr;56(4):949-55. doi: 10.1128/aem.56.4.949-955.1990.
10
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J Comp Pathol. 1992 Feb;106(2):137-52. doi: 10.1016/0021-9975(92)90043-t.