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神经可塑性。中枢神经系统损伤后恢复的关键。

Neuroplasticity. Key to recovery after central nervous system injury.

作者信息

Dobkin B H

机构信息

Department of Neurology, University of California, Los Angeles, School of Medicine 90024-6975.

出版信息

West J Med. 1993 Jul;159(1):56-60.

PMID:8351906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1022159/
Abstract

After an injury to the central nervous system, physical and cognitive impairments and disabilities often abate. These gains may be partly mediated by mechanisms that allow reorganizing of the structure and function within gray and white matter. The potential to enhance neurologic recovery by manipulating the brain and spinal cord must now be considered in clinical practice. Today's rehabilitation routines may not encourage maximum recovery. Indeed, some commonly used physical and pharmacologic methods could inhibit the restoration of motor activities such as walking. On the other hand, therapies that use our expanding knowledge of neuroplasticity could lead to better results for patients.

摘要

中枢神经系统损伤后,身体和认知障碍及残疾往往会减轻。这些改善可能部分由允许灰质和白质内结构和功能重组的机制介导。现在临床实践中必须考虑通过操纵大脑和脊髓来增强神经恢复的潜力。当今的康复常规可能无法促进最大程度的恢复。事实上,一些常用的物理和药物方法可能会抑制诸如行走等运动活动的恢复。另一方面,利用我们不断扩展的神经可塑性知识的疗法可能会给患者带来更好的效果。

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