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巨细胞动脉炎中的脉络膜无灌注

Choroidal nonperfusion in giant cell arteritis.

作者信息

Quillen D A, Cantore W A, Schwartz S R, Brod R D, Sassani J W

机构信息

Department of Ophthalmology, Penn State University College of Medicine, Hershey, Pennsylvania.

出版信息

Am J Ophthalmol. 1993 Aug 15;116(2):171-5. doi: 10.1016/s0002-9394(14)71281-4.

Abstract

A 68-year-old man had visual loss secondary to isolated choroidal nonperfusion as a clinical manifestation of giant cell arteritis. Ophthalmoscopy disclosed scattered yellow-white lesions at the level of the retinal pigment epithelium in the posterior pole of the right eye. Intravenous fluorescein angiography demonstrated marked delay in choroidal filling of the macula in the right eye. There was no ophthalmoscopic or angiographic evidence of anterior ischemic optic neuropathy or central retinal artery occlusion. After approximately 72 hours of intravenous corticosteroid therapy, the patient's visual acuity improved and repeat intravenous fluorescein angiography showed normal choroidal circulation. Isolated choroidal ischemia is a potential cause of reversible visual loss in patients with giant cell arteritis.

摘要

一名68岁男性因巨细胞动脉炎临床表现为孤立性脉络膜灌注不良继发视力丧失。检眼镜检查发现右眼后极视网膜色素上皮层有散在的黄白色病变。静脉注射荧光素血管造影显示右眼黄斑区脉络膜充盈明显延迟。没有检眼镜或血管造影证据表明存在前部缺血性视神经病变或视网膜中央动脉阻塞。经过约72小时的静脉注射皮质类固醇治疗,患者视力改善,重复静脉注射荧光素血管造影显示脉络膜循环正常。孤立性脉络膜缺血是巨细胞动脉炎患者可逆性视力丧失的一个潜在原因。

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