Vine M F, Hulka B S, Margolin B H, Truong Y K, Hu P C, Schramm M M, Griffith J D, McCann M, Everson R B
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-7400.
Am J Public Health. 1993 Sep;83(9):1335-8. doi: 10.2105/ajph.83.9.1335.
Cotinine levels in the semen, urine, and blood of 88 male smokers and nonsmokers, aged 18 to 35, were analyzed via radioimmunoassay. Detectable cotinine levels were found in all three body fluids, and cotinine levels in all three fluids were highly correlated. Cotinine levels in semen and blood were of similar magnitude; cotinine levels in urine were an order of magnitude or more higher. In all three fluids, cotinine levels increased with an increase in cigarette smoke exposure.
通过放射免疫分析法对88名年龄在18至35岁之间的男性吸烟者和非吸烟者的精液、尿液和血液中的可替宁水平进行了分析。在所有三种体液中均检测到了可替宁水平,且三种体液中的可替宁水平高度相关。精液和血液中的可替宁水平相近;尿液中的可替宁水平则高出一个数量级或更多。在所有三种体液中,可替宁水平均随香烟烟雾暴露量的增加而升高。