Collman J P, Zhang X, Lee V J, Uffelman E S, Brauman J I
Department of Chemistry, Stanford University, CA 94305.
Science. 1993 Sep 10;261(5127):1404-11. doi: 10.1126/science.8367724.
Recent progress in regioselective and enantioselective epoxidations catalyzed by metalloporphyrins is discussed here, with an explanation of the biomimetic antecedents of this area and its relevance to synthetic applications. Classification of the catalysts that have been studied allows useful conclusions to be drawn about the development of this field. In particular, both the most promising biomimetic and practical catalysts have arisen from systems that can be systematically modified by convenient synthetic methodology.
本文讨论了金属卟啉催化的区域选择性和对映选择性环氧化反应的最新进展，并解释了该领域的仿生学先例及其与合成应用的相关性。对已研究的催化剂进行分类有助于得出有关该领域发展的有用结论。特别是，最有前景的仿生催化剂和实用催化剂均来自可以通过便捷的合成方法进行系统修饰的体系。
