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Nucleotide sequence of the envelope protein gene of the tick-borne flavivirus, Kumlinge A52.

作者信息

Whitby J E, Jennings A D, Barrett A D

机构信息

School of Biological Sciences, University of Surrey, Guildford, UK.

出版信息

Virus Genes. 1993 Jun;7(2):145-9. doi: 10.1007/BF01702394.

DOI:10.1007/BF01702394
PMID:8367941
Abstract

The envelope protein gene of the tick-borne flavivirus, Kumlinge A52, the proto-type Finnish strain, has been amplified and sequenced.* The nucleotide and deduced amino acid sequence has been analyzed and compared with the closely related tick-borne encephalitis (TBE) virus, Western subtype, strain Neudoerfl, isolated in Austria. Although these two virus strains were isolated 12 years apart from different hosts and in different countries, the envelope proteins only differed by a single amino acid. It is likely, therefore, that strong selection pressures against antigenic variation exist. The possible reasons for this are discussed.

摘要

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本文引用的文献

1
FURTHER STUDIES ON ANTIGENIC RELATIONSHIPS AMONG THE VIRUSES OF THE GROUP B TICK-BORNE COMPLEX.关于B组蜱传病毒复合体中病毒间抗原关系的进一步研究
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Complete nucleotide sequence of the Japanese encephalitis virus genome RNA.日本脑炎病毒基因组RNA的完整核苷酸序列。
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Sequence of the dengue-1 virus genome in the region encoding the three structural proteins and the major nonstructural protein NS1.登革热1型病毒基因组中编码三种结构蛋白和主要非结构蛋白NS1的区域序列。
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Sequence of the structural proteins of tick-borne encephalitis virus (western subtype) and comparative analysis with other flaviviruses.蜱传脑炎病毒（西方亚型）结构蛋白序列及与其他黄病毒的比较分析。
Virology. 1988 Sep;166(1):197-205. doi: 10.1016/0042-6822(88)90161-4.
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Partial nucleotide sequence and deduced amino acid sequence of the structural proteins of dengue virus type 2, New Guinea C and PUO-218 strains.
J Gen Virol. 1988 Jun;69 ( Pt 6):1391-8. doi: 10.1099/0022-1317-69-6-1391.
6
Molecular cloning and complete nucleotide sequence of the genome of Japanese encephalitis virus Beijing-1 strain.日本脑炎病毒北京-1株基因组的分子克隆及全核苷酸序列
Virus Genes. 1988 Jun;1(3):305-17. doi: 10.1007/BF00572709.
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Evidence for antigenic stability of tick-borne encephalitis virus by the analysis of natural isolates.通过对自然分离株的分析获得蜱传脑炎病毒抗原稳定性的证据。
J Gen Virol. 1987 Mar;68 ( Pt 3):859-64. doi: 10.1099/0022-1317-68-3-859.
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Nucleotide sequence and deduced amino acid sequence of the structural proteins of dengue type 2 virus, Jamaica genotype.2型登革病毒牙买加基因型结构蛋白的核苷酸序列及推导的氨基酸序列
Virology. 1986 Dec;155(2):365-77. doi: 10.1016/0042-6822(86)90200-x.
9
Murray Valley encephalitis virus field strains from Australia and Papua New Guinea: studies on the sequence of the major envelope protein gene and virulence for mice.来自澳大利亚和巴布亚新几内亚的墨累谷脑炎病毒野外毒株：主要包膜蛋白基因序列及对小鼠毒力的研究
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Nucleotide sequence of dengue 2 RNA and comparison of the encoded proteins with those of other flaviviruses.登革2型病毒RNA的核苷酸序列以及其编码蛋白与其他黄病毒编码蛋白的比较。
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