Moran C A, Suster S, Carter D
Department of Surgical Pathology, Yale-New Haven, Conn.
Arch Pathol Lab Med. 1993 Sep;117(9):914-7.
Four cases of laryngeal chondrosarcoma are presented. The patients' ages ranged from 60 to 75 years; one was a man and three were women. Two of the tumors arose in the thyroid cartilage, one in the cricoid cartilage, and one in the left arytenoid cartilage. A rapid fatal course with pulmonary and cerebral metastases was observed for the tumor arising in the arytenoid cartilage that histologically corresponded to a myxoid chondrosarcoma. The other three cases corresponded to low-grade, well-differentiated chondrosarcomas of the hyaline type, and the patients were alive and free of recurrence or metastases 3 to 6 years following total and partial laryngectomy. A review of the literature on the topic and the importance of assessing histologic grade, size, and location in the evaluation of these neoplasms is discussed.
本文报告了4例喉软骨肉瘤病例。患者年龄在60至75岁之间；1例为男性，3例为女性。其中2例肿瘤发生于甲状软骨，1例发生于环状软骨，1例发生于左杓状软骨。发生于杓状软骨的肿瘤组织学上符合黏液样软骨肉瘤，观察到其病程进展迅速并伴有肺和脑转移。其他3例为低度、高分化的透明型软骨肉瘤，患者在全喉或部分喉切除术后3至6年存活，无复发或转移。本文还讨论了该主题的文献综述以及在评估这些肿瘤时评估组织学分级、大小和位置的重要性。
