Nikawa H, Hayashi S, Nikawa Y, Hamada T, Samaranayake L P
Department of Prosthetic Dentistry, Hiroshima University School of Dentistry, Japan.
Arch Oral Biol. 1993 Jul;38(7):631-4. doi: 10.1016/0003-9969(93)90132-6.
The interactions between pellicles derived from saliva, serum, mucin and lysozyme deposited on lining material (tissue conditioner) and Candida albicans were investigated by monitoring pH changes associated with protein-free and protein-coated lining material and by ultrastructural observations of yeast colonization. No significant differences in pH reduction between culture media in contact with the protein-free, control lining materials and those coated with saliva, serum or mucin were observed after 120 h of incubation. However, scanning electron microscopy revealed that much greater numbers of the yeasts colonized the saliva- or serum-coated lining material than the lysozyme-, mucin-coated or control material. Hyphal invasion was observed in saliva-coated lining material. These results suggested that denture pellicle derived from saliva and/or serum may potentiate candidal colonization of denture lining materials.
通过监测与无蛋白和蛋白包被的衬里材料（组织调理剂）相关的pH变化以及对酵母定植的超微结构观察，研究了沉积在衬里材料（组织调理剂）上的源自唾液、血清、粘蛋白和溶菌酶的薄膜与白色念珠菌之间的相互作用。孵育120小时后，未观察到与无蛋白对照衬里材料接触的培养基和涂有唾液、血清或粘蛋白的培养基之间在pH降低方面有显著差异。然而，扫描电子显微镜显示，与溶菌酶、粘蛋白包被的材料或对照材料相比，有更多数量的酵母有定植在唾液或有血清包被的衬里材料上。在唾液包被的衬里材料中观察到了菌丝入侵。这些结果表明，源自唾液和/或血清的义齿薄膜可能会增强义齿衬里材料上念珠菌的定植。
