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小脑前叶传入至前间位核的电生理及辣根过氧化物酶研究。I. 攀缘纤维系统。

Electrophysiological and horseradish peroxidase studies of precerebellar afferents to the nucleus interpositus anterior. I. Climbing fiber system.

作者信息

Kitai S T, McCrea R A, Preston R J, Bishop G A

出版信息

Brain Res. 1977 Feb 18;122(2):197-214. doi: 10.1016/0006-8993(77)90289-x.

DOI:10.1016/0006-8993(77)90289-x
PMID:837228
Abstract

The input to the nucleus interpositus anterior (NIA) of the cat from the inferior olive (IO) was studied by stimulating the IO while recording intracellularly from the NIA, and by the retrograde transport of horseradish peroxidase (HRP). Stimulation of the IO evoked monosynaptic EPSPs in NIA neurons. The cells labeled in the IO following electrophoretic and pressure injection of HRP into NIA were located in the rostral parts of the dorsal and medial accessory olive. Stimulation of the IO also polysynaptically evoked an IPSP and a late disinhibitory depolarization. Data were presented which indicated that these potentials were mediated by the Purkinje cells of the cerebellar cortex.

摘要

通过在细胞内记录猫的前间位核(NIA)时刺激下橄榄核(IO),以及利用辣根过氧化物酶(HRP)的逆行运输,对猫从下橄榄核到前间位核的输入进行了研究。刺激下橄榄核在NIA神经元中诱发单突触兴奋性突触后电位(EPSP)。在将HRP电泳和压力注射到NIA后,在下橄榄核中标记的细胞位于背侧和内侧副橄榄核的吻侧部分。刺激下橄榄核还多突触地诱发抑制性突触后电位(IPSP)和晚期去抑制性去极化。所呈现的数据表明,这些电位是由小脑皮质的浦肯野细胞介导的。

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Electrophysiological and horseradish peroxidase studies of precerebellar afferents to the nucleus interpositus anterior. I. Climbing fiber system.小脑前叶传入至前间位核的电生理及辣根过氧化物酶研究。I. 攀缘纤维系统。
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