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[应用酶联免疫吸附测定法检测变性者和同性恋者单纯疱疹病毒2型(HSV-2)的IgG和IgM]

[Demonstration of herpes simplex virus (HSV)-2 IgG and IgM using ELISA in transsexuals and homosexuals].

作者信息

Cengiz A T, Kendi O, Kiyan M, Bilge Y, Uğurel S, Tümer A R

机构信息

Ankara Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali.

出版信息

Mikrobiyol Bul. 1993 Jan;27(1):46-51.

PMID:8380622
Abstract

In this study, the sera of 12 cases of transsexual with vaginoplasty and 15 cases of homosexual have been investigated with ELISA from the view point of HSV-2 IgG and IgM antibodies. Twenty-five cases were within the 18-26 age groups and the other 2 transsexuals were 36 years old. Our studying group have no significant clinical pathology. In all the 27 cases of transsexual and homosexual have been found to be positive for HSV-2 IgG. In 7 cases, HSV-2 IgM have been found positive, the other 20 cases have been found negative results. In the one third of the transsexuals and one fifth of the transsexuals HSV-2 IgG have been found positive. Twenty-six per cent of seropositivity in transsexuals and homosexuals show that they form significant risk group from the point of view of HSV-2 infection.

摘要

在本研究中,从HSV-2 IgG和IgM抗体的角度,用酶联免疫吸附测定法(ELISA)对12例接受阴道成形术的变性者和15例同性恋者的血清进行了检测。25例在18至26岁年龄组,另外2例变性者为36岁。我们的研究组无明显临床病理表现。在所有27例变性者和同性恋者中,均发现HSV-2 IgG呈阳性。7例HSV-2 IgM呈阳性,另外20例结果为阴性。在三分之一的变性者和五分之一的同性恋者中发现HSV-2 IgG呈阳性。变性者和同性恋者中26%的血清阳性表明,从HSV-2感染的角度来看,他们构成了显著的风险群体。

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HSV-2 serology can be predictive of HIV epidemic potential and hidden sexual risk behavior in the Middle East and North Africa.HSV-2 血清学检测可预测中东和北非的 HIV 流行潜力和隐匿性性风险行为。
Epidemics. 2010 Dec;2(4):173-82. doi: 10.1016/j.epidem.2010.08.003. Epub 2010 Sep 15.