Bennett N T, Schultz G S
Department of Surgery, University of Florida, Gainesville.
Am J Surg. 1993 Jul;166(1):74-81. doi: 10.1016/s0002-9610(05)80589-6.
Wound healing is a complex biologic process that involves the integration of inflammation, mitosis, angiogenesis, synthesis, and remodeling of the extracellular matrix. Part II of this two-part series reviews the results of experiments that indicate that growth factors and their receptors regulate key aspects of soft and hard tissue repair. Results of clinical studies are also reviewed that demonstrate that growth factor treatment accelerates healing of normal tissues and promotes healing of impaired wounds.
伤口愈合是一个复杂的生物学过程，涉及炎症、有丝分裂、血管生成、细胞外基质的合成与重塑。这个两部分系列的第二部分回顾了实验结果，这些结果表明生长因子及其受体调节软组织和硬组织修复的关键方面。还回顾了临床研究结果，这些结果表明生长因子治疗可加速正常组织的愈合并促进受损伤口的愈合。
