Smyth A G, Ward-Booth R P, Avery B S, To E W
Regional Plastic and Jaw Surgery Unit, Wordsley Hospital, West Midlands.
Br J Oral Maxillofac Surg. 1993 Aug;31(4):230-5. doi: 10.1016/0266-4356(93)90145-m.
Oral malignant melanoma is fortunately a rare lesion. However the actual incidence in the population at present is unknown but may be increasing. The overall prognosis remains poor despite more radical surgery with adjuvant radiotherapy, chemotherapy and immunotherapy. The clinical presentation of oral malignant melanoma can vary widely from a typically pigmented macular or proliferative lesion to a non-pigmented soft vascular tumour; single or multiple, primary or metastatic. Our experience of five patients with malignant melanoma of the oral cavity is presented and the management of such lesions discussed.
幸运的是，口腔恶性黑色素瘤是一种罕见的病变。然而，目前人群中的实际发病率尚不清楚，但可能正在上升。尽管采用了更激进的手术，并辅以放疗、化疗和免疫疗法，总体预后仍然很差。口腔恶性黑色素瘤的临床表现差异很大，从典型的色素沉着斑或增生性病变到无色素的柔软血管性肿瘤；可为单发或多发，原发性或转移性。本文介绍了我们对5例口腔恶性黑色素瘤患者的治疗经验，并讨论了此类病变的处理方法。
