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足部间歇性充气加压对动脉疾病微循环功能的影响。

Effects of intermittent pneumatic compression of the foot on the microcirculatory function in arterial disease.

作者信息

Abu-Own A, Cheatle T, Scurr J H, Coleridge Smith P D

机构信息

Department of Surgery, University College and Middlesex School of Medicine, London, U.K.

出版信息

Eur J Vasc Surg. 1993 Sep;7(5):488-92. doi: 10.1016/s0950-821x(05)80358-5.

DOI:10.1016/s0950-821x(05)80358-5
PMID:8405490
Abstract

OBJECTIVE

The venous pump of the foot assists blood returning to the heart. The aim of this study was to evaluate the effect of mechanical activation of the foot pump on the microcirculation of the skin in patients with peripheral occlusive arterial disease.

DESIGN

Single parallel group comparing patients with arterial disease to normal control subjects.

SETTING

Department of Surgery, the University College and Middlesex Hospital, London, U.K.

SUBJECTS AND MATERIALS

15 patients with peripheral occlusive arterial disease and 15 control subjects. A pneumatic impulse foot pump was applied to the foot.

OUTCOME MEASURES

The Laser Doppler flux (LDF) and transcutaneous oxygen tension (tcPO2) were measured on the big toe with the subject supine, before, during and after a 10 min period of foot pumping. The study was repeated with the subject sitting.

RESULTS

On sitting there is a fall in LDF and rise in tcPO2. Application of intermittent pneumatic compression of the foot in the sitting position resulted in an increase in LDF. In patients, the median percentage increase was 57% and the median difference was 82 arbitrary units (AU) (95% CI 60-130, p < 0.001). In controls, the median percentage increase was 66% and the median difference was 124 AU (95% CI 73-275 p < 0.001). There was a corresponding "further" increase in tcPO2 in both groups of subjects. In patients, the median percentage increase was 8%, in controls the median percentage increase was 10% p < 0.01).

CONCLUSION

We conclude that intermittent pneumatic compression of the foot in the dependent position increases LDF and tcPO2.

摘要

目的

足部静脉泵有助于血液回流至心脏。本研究旨在评估机械激活足部泵对周围闭塞性动脉疾病患者皮肤微循环的影响。

设计

将动脉疾病患者与正常对照受试者进行单平行组比较。

设置

英国伦敦大学学院和米德尔塞克斯医院外科。

受试者和材料

15例周围闭塞性动脉疾病患者和15名对照受试者。使用气动脉冲足部泵作用于足部。

观察指标

在受试者仰卧位时,于足部泵动10分钟前、期间和之后,测量其大脚趾处的激光多普勒血流(LDF)和经皮氧分压(tcPO2)。研究在受试者坐位时重复进行。

结果

坐位时LDF下降,tcPO2升高。在坐位时对足部进行间歇性气动加压可使LDF增加。在患者中,中位百分比增加为57%,中位差值为82任意单位(AU)(95%CI 60 - 130,p < 0.001)。在对照组中,中位百分比增加为66%,中位差值为124 AU(95%CI 73 - 275,p < 0.001)。两组受试者的tcPO2均有相应的“进一步”升高。在患者中,中位百分比增加为8%,在对照组中,中位百分比增加为10%(p < 0.01)。

结论

我们得出结论,在足部处于下垂位置时对其进行间歇性气动加压可增加LDF和tcPO2。

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