Garner W L, Thomson P D, Moore N P, Rodriguez J L, Smith D J
Department of Surgery, University of Michigan School of Medicine, Ann Arbor.
J Burn Care Rehabil. 1993 Jul-Aug;14(4):458-60. doi: 10.1097/00004630-199307000-00011.
Excisional therapy often results in large-volume blood loss. Triglycyl-lysine-vasopressin selectively decreases dermal blood flow and therefore was tested for efficacy in limiting intraoperative blood loss in a series of patients undergoing excisional therapy. Ten patients with symmetric injuries were treated with intravenous triglycyl-lysine-vasopressin after excision of half of their burn wound. Blood loss, which was quantified by weighing sponges used to absorb shed blood, was significantly decreased after treatment. Triglycyl-lysine-vasopressin treatment was safe and effective and should be considered in cases when large-volume blood loss is expected.
切除疗法常常导致大量失血。三甘氨酰赖氨酸加压素可选择性地减少皮肤血流量，因此在一系列接受切除疗法的患者中对其限制术中失血的疗效进行了测试。十名对称性损伤患者在切除一半烧伤创面后接受了静脉注射三甘氨酰赖氨酸加压素治疗。通过称量用于吸收流出血液的海绵来量化失血量，治疗后失血量显著减少。三甘氨酰赖氨酸加压素治疗安全有效，在预计会出现大量失血的情况下应予以考虑。
