鼠适应血凝性脑脊髓炎病毒的嗜神经性
Neurotropism of mouse-adapted haemagglutinating encephalomyelitis virus.
作者信息
Yagami K, Izumi Y, Kajiwara N, Sugiyama F, Sugiyama Y
机构信息
Laboratory Animal Research Center, University of Tsukuba, Ibaraki, Japan.
出版信息
J Comp Pathol. 1993 Jul;109(1):21-7. doi: 10.1016/s0021-9975(08)80237-x.
Abstract
The propagation of a mouse-adapted strain (67N) of haemagglutinating encephalomyelitis virus in infected mice and murine cells was examined by viral re-isolation and immunostaining. Viral propagation was strictly limited to the neurons and to an established line of neuroblastoma cells in in-vivo and in-vitro experiments. These results provide adequate evidence that this virus is neurotropic.
摘要
通过病毒再分离和免疫染色，研究了血凝性脑脊髓炎病毒的小鼠适应株（67N）在感染小鼠和鼠细胞中的增殖情况。在体内和体外实验中，病毒增殖严格局限于神经元和已建立的神经母细胞瘤细胞系。这些结果提供了充分的证据，证明这种病毒具有嗜神经性。
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本文引用的文献
1
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Brain Res. 1981 May 18;212(2):393-402. doi: 10.1016/0006-8993(81)90471-6.
2
Inducement of cytopathic changes and plaque formation by porcine haemagglutinating encephalomyelitis virus.猪血凝性脑脊髓炎病毒诱导细胞病变和蚀斑形成
Vet Microbiol. 1983 Nov;8(6):521-30. doi: 10.1016/0378-1135(83)90001-9.
3
Chronic central nervous system demyelination in mice after JHM virus infection.JHM病毒感染后小鼠的慢性中枢神经系统脱髓鞘
Neurology. 1981 Jan;31(1):38-44. doi: 10.1212/wnl.31.1.38.
4
5
6
Characteristics of a coronavirus (strain 67N) of pigs.猪冠状病毒（67N毒株）的特性
Am J Vet Res. 1972 Feb;33(2):297-308.
7
8
Pathogenesis of haemagglutinating encephalomyelitis virus (HEV) in mice experimentally infected by different routes.经不同途径实验性感染小鼠的血凝性脑脊髓炎病毒（HEV）的发病机制
J Comp Pathol. 1986 Nov;96(6):645-57. doi: 10.1016/0021-9975(86)90061-7.
9
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J Comp Pathol. 1989 Apr;100(3):305-12. doi: 10.1016/0021-9975(89)90108-4.
10
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J Comp Pathol. 1989 Feb;100(2):119-28. doi: 10.1016/0021-9975(89)90122-9.
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