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顺铂和盐酸表柔比星、丝裂霉素C-碘海醇-碘油乳剂(EMILE)超选择性支气管动脉灌注治疗肺门部肺腺癌:初步临床经验

[Superselective bronchial arterial infusion therapy with cisplatin and epirubicin hydrochloride, mitomycin C-iohexol-Lipiodol emulsion (EMILE) for hilar lung adenocarcinoma: preliminary clinical experience].

作者信息

Kanematsu M, Yamawaki Y, Matsui E, Mochizuki R, Goto H, Asada S, Imaeda T, Shibayama M, Doi H

机构信息

Department of Radiology, Gifu University School of Medicine.

出版信息

Nihon Igaku Hoshasen Gakkai Zasshi. 1993 Sep 25;53(9):1073-5.

PMID:8414933
Abstract

A case of hilar lung adenocarcinoma was treated by superselective bronchial arterial infusion therapy with cisplatin and epirubicin hydrochloride, mitomycin C-iohexol-Lipiodol emulsion (EMILE) using Tracker -18 infusion catheter. The tumor size was reduced on follow-up CT scans. However, EMILE was also distributed to nontumorous lung tissues around the tumor, and a shrinkage of the right upper lobe and elevations of the right hilus and diaphragm followed. No major complaints and clinical complications during and after the treatment occurred. This therapy was safe and effective for local tumor reduction in a case of hilar lung adenocarcinoma.

摘要

1例肺门部肺腺癌患者采用Tracker -18输注导管,行顺铂、盐酸表柔比星及丝裂霉素C-碘海醇-碘油乳剂(EMILE)超选择性支气管动脉灌注治疗。随访CT扫描显示肿瘤大小缩小。然而,EMILE也分布到肿瘤周围的非肿瘤性肺组织,随后右上叶出现萎缩,右肺门和膈肌抬高。治疗期间及治疗后未出现严重不适和临床并发症。该治疗方法对于肺门部肺腺癌局部肿瘤缩小是安全有效的。

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