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[脑积水患儿脑脊液系统减压效果的临床生理分析]

[Clinico-physiologic analysis of the effect of decompressing the cerebrospinal fluid system in children with hydrocephalus].

作者信息

Anzimirov V L, Mareeva T G, Simernitskiĭ B P, Spirin B G

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1977(1):31-5.

PMID:842259
Abstract

Changes in vascular tonicity and blood filling in the brain were studied in 26 children with occlusive hydrocephalus during ventricular punctures and following surgical elimination of the occlusion. The nature of the reactive changes in the tonicity and blood filling of the cerebral and peripheral vessels was found to be different in response to the draining of the CSF system depending on the level of thebrain lesion. Following ventricular punctures with CSF draining the majority of the examined demonstrated a normalization of their elevated tonicity of the cerebral vessels and a disappearance of hampered venous drainage. The dynamics of the vascular responses developing under the effect of dehydration agents is characterized by the maximum response 30-50 min following the administration of the drug and by a gradual restoration of the initial state some 2-2 1/2 hours later.

摘要

在26例梗阻性脑积水患儿进行脑室穿刺时以及手术解除梗阻后,研究了脑部血管张力和血液充盈情况。结果发现,根据脑部病变的程度不同,脑脊液系统引流时,脑血管和外周血管张力及血液充盈的反应性变化性质有所不同。在进行脑脊液引流的脑室穿刺后,大多数受检者显示其升高的脑血管张力恢复正常,静脉引流受阻现象消失。脱水剂作用下血管反应的动态变化特点是,给药后30 - 50分钟出现最大反应,约2 - 2.5小时后逐渐恢复至初始状态。

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