Noller H F
Sinsheimer Laboratories, University of California, Santa Cruz 95064.
FASEB J. 1993 Jan;7(1):87-9. doi: 10.1096/fasebj.7.1.8422979.
The extent to which ribosomal RNA is directly involved in the function of ribosomes has important implications for both the mechanism of translation and the molecular origins of life. Detailed evidence has accumulated that places the anticodon and acceptor ends of tRNA in close proximity to conserved features of rRNA in the ribosome. Recent studies are providing evidence that these features are important for ribosomal function.
核糖体RNA直接参与核糖体功能的程度，对翻译机制和生命的分子起源都具有重要意义。已有大量详细证据表明，tRNA的反密码子和受体末端与核糖体中rRNA的保守特征紧密相邻。最近的研究正在提供证据，表明这些特征对核糖体功能很重要。
