Ritter L L, Klein B E, Klein R, Mares-Perlman J A
Department of Ophthalmology, University of Wisconsin Medical School, Madison 53792-3220.
Arch Ophthalmol. 1993 Jan;111(1):113-7. doi: 10.1001/archopht.1993.01090010117037.
The relationship between alcohol use and lens opacities was examined in a large (N = 4926) population-based study of adults aged 43 to 86 years in Beaver Dam, Wis. These data were collected from 1988 to 1990. Alcohol history was determined by a standardized questionnaire. Prevalence and severity of cataract were determined by masked grading of photographs obtained using a slit-lamp camera and retroillumination. A history of heavy drinking was related to more severe nuclear sclerotic, cortical, and posterior subcapsular opacities (odds ratios, 1.34, 1.38, and 1.57, respectively). These relationships remained after adjusting for other risk factors such as smoking. Moderate liquor consumption was associated with less severe nuclear sclerosis (odds ratio, 0.81). Participants who drank wine had less severe nuclear sclerosis (odds ratio, 0.84) and cortical opacities (odds ratio, 0.84) than those who did not. Increased consumption of beer was related to increased risk of cortical opacities.
在威斯康星州比弗代尔姆市开展的一项针对43至86岁成年人的大型（N = 4926）基于人群的研究中，对饮酒与晶状体混浊之间的关系进行了调查。这些数据于1988年至1990年收集。饮酒史通过标准化问卷确定。白内障的患病率和严重程度通过使用裂隙灯相机和后照法获得的照片进行盲法分级来确定。大量饮酒史与更严重的核性硬化、皮质和后囊下混浊相关（比值比分别为1.34、1.38和1.57）。在对吸烟等其他风险因素进行调整后，这些关系依然存在。适量饮用白酒与较轻的核性硬化相关（比值比为0.81）。饮用葡萄酒的参与者比不饮用葡萄酒的参与者核性硬化（比值比为0.84）和皮质混浊（比值比为0.84）程度更轻。啤酒消费量增加与皮质混浊风险增加相关。
