Lundberg I, Gustavsson A, Holmberg B, Molina G, Westerholm P
Department of Occupational Health, Karolinska Hospital, Stockholm, Sweden.
Am J Ind Med. 1993 Feb;23(2):313-9. doi: 10.1002/ajim.4700230208.
The mortality pattern and the cancer incidence were investigated among 717 men who had been employed for at least 3 months during 1964-1974 in three Swedish PVC-processing plants. The mortality was followed 1964-1986 and the cancer incidence 1964-1984. Expected figures were calculated from Swedish national rates. Among Swedish citizens, the observed mortality and cancer incidence was close to the expected in most diagnoses. Among immigrants, mostly from Finland, there was a marked excess of circulatory deaths. This finding was probably due to the higher incidence of coronary mortality in Finland compared to Sweden. In the whole cohort, five cases of malignant melanoma had occurred as compared to 1.5 expected (SMR = 3.4, 95% confidence limit 1.1-7.9). This may be due to chance but merits further investigation since an increased incidence of malignant melanoma has previously been found among Norwegian PVC-manufacturing workers.
对1964年至1974年期间在瑞典三家聚氯乙烯加工厂工作至少3个月的717名男性的死亡率模式和癌症发病率进行了调查。随访了1964年至1986年的死亡率以及1964年至1984年的癌症发病率。预期数据根据瑞典全国发病率计算得出。在瑞典公民中,大多数诊断的观察到的死亡率和癌症发病率接近预期。在主要来自芬兰的移民中,循环系统疾病死亡明显过多。这一发现可能是由于芬兰的冠状动脉死亡率高于瑞典。在整个队列中,发生了5例恶性黑色素瘤,而预期为1.5例(标准化死亡比=3.4,95%置信区间1.1-7.9)。这可能是偶然现象,但值得进一步调查,因为此前在挪威聚氯乙烯制造工人中发现恶性黑色素瘤发病率有所上升。