Greenstein V C, Thomas S R, Blaustein H, Koenig K, Carr R E
Department of Ophthalmology, New York University Medical Center, New York.
Optom Vis Sci. 1993 Jan;70(1):18-23. doi: 10.1097/00006324-199301000-00005.
Previous studies have shown that S-cone pathway sensitivity is selectively decreased in the early stages of diabetic retinopathy. In the present study, rod system sensitivity was evaluated in a group of diabetic patients using psychophysical techniques. The course of dark adaptation was first determined, then absolute thresholds were measured in the horizontal and vertical meridians. For all patients, although the recovery of the initial portions of rod dark adaptation were normal, absolute thresholds were increased in both the horizontal and vertical meridians. The findings provide evidence that patients with early diabetic retinopathy show a generalized dysfunction of the rod system.
先前的研究表明，在糖尿病视网膜病变的早期阶段，S视锥细胞通路敏感性会选择性降低。在本研究中，使用心理物理学技术对一组糖尿病患者的视杆系统敏感性进行了评估。首先确定暗适应过程，然后测量水平和垂直子午线的绝对阈值。对于所有患者，尽管视杆暗适应初始部分的恢复正常，但水平和垂直子午线的绝对阈值均升高。这些发现提供了证据，表明早期糖尿病视网膜病变患者存在视杆系统的广泛性功能障碍。
