Alexander K R, Fishman G A
Br J Ophthalmol. 1984 Aug;68(8):561-9. doi: 10.1136/bjo.68.8.561.
The time course of rod dark adaptation was measured in 12 patients and carriers of retinitis pigmentosa (RP). In contrast to previous studies the rod absolute threshold was determined prior to any exposure to the bleaching light. For seven of the patients and carriers the recovery of rod sensitivity to the prebleach level was prolonged, with the delay ranging from mild to severe. The prolongation appeared to be limited to the late phase of bleaching recovery; the early portion of rod dark adaptation, measured following a weak bleach, was normal. These results suggest a selective impairment in the processes underlying rod dark adaptation in some patients with RP.
对12名视网膜色素变性（RP）患者及携带者的视杆细胞暗适应时间进程进行了测量。与之前的研究不同，视杆细胞绝对阈值是在未暴露于漂白光之前测定的。7名患者及携带者的视杆细胞敏感度恢复至漂白前水平的过程延长，延迟程度从轻度到重度不等。这种延长似乎仅限于漂白恢复的后期阶段；在轻度漂白后测量的视杆细胞暗适应早期部分是正常的。这些结果表明，部分RP患者视杆细胞暗适应背后的过程存在选择性损伤。
