Greenstein V, Sarter B, Hood D, Noble K, Carr R
Department of Ophthalmology, New York University Medical Center, New York 10016.
Invest Ophthalmol Vis Sci. 1990 Jun;31(6):1008-14.
Measures of hue discrimination and M (green) and S (blue) cone pathway sensitivities were compared in a group of 24 diabetics with either early background retinopathy or no retinopathy. The Farnsworth-Munsell 100-hue test was used to measure hue discrimination, and a two-color increment threshold technique was used to measure S and M cone pathway sensitivities. The results were compared to the level of diabetic retinopathy, to the degree of macular edema, and to the duration of the disease. No significant correlation was found between the Farnsworth-Munsell 100-hue error scores and the level of retinopathy; S cone pathway sensitivity loss, however, correlated significantly with both the level of retinopathy and the degree of macular edema. Our results indicate that measurements of S cone pathway sensitivity using an increment threshold technique provide a more sensitive method than hue discrimination for detecting color vision deficits in early diabetic retinopathy.
在一组24名患有早期背景性视网膜病变或无视网膜病变的糖尿病患者中，对色调辨别以及M（绿色）和S（蓝色）视锥细胞通路敏感性的测量结果进行了比较。使用法恩斯沃思-芒塞尔100色调测试来测量色调辨别能力，并采用双色增量阈值技术来测量S和M视锥细胞通路的敏感性。将结果与糖尿病视网膜病变的程度、黄斑水肿的程度以及疾病持续时间进行了比较。在法恩斯沃思-芒塞尔100色调误差评分与视网膜病变程度之间未发现显著相关性；然而，S视锥细胞通路敏感性丧失与视网膜病变程度和黄斑水肿程度均显著相关。我们的结果表明，使用增量阈值技术测量S视锥细胞通路敏感性，比色调辨别能提供一种更敏感的方法来检测早期糖尿病视网膜病变中的色觉缺陷。
