Dostál C, Iványi D, Macurová H, Hána I, Strejcek J
Ann Rheum Dis. 1977 Feb;36(1):83-5. doi: 10.1136/ard.36.1.83.
Forty-five patients suffering from systemic lupus erythematosus were studied in respect of their serologically defined HLA antigens. HLA-B8 antigen was found in 37-8% of patients as compared to 22% of controls. Individuals carrying the HLA-B8 antigen have a 2-15 times greater risk of developing systemic lupus erythematosus than those not carrying this antigen.
对45例系统性红斑狼疮患者进行了血清学定义的HLA抗原研究。发现37.8%的患者存在HLA - B8抗原,而对照组为22%。携带HLA - B8抗原的个体患系统性红斑狼疮的风险是未携带该抗原个体的2至15倍。