Nippon Ganka Gakkai Zasshi. 1993 Jan;97(1):103-8.
The present study is the second report using the data of the epidemiological survey of retinopathy of prematurity (ROP) obtained during the 2 year period 1986-1987 in Aichi Prefecture. To study ROP we have used birthweight and gestational age for estimation of infants' prematurity. These two parameters were found to have a very close relation with the incidence of ROP. Although gestational age is close to the embryonic age, birthweight is greatly influenced by intrauterine environmental factors. To confirm the importance of using birthweight, the relationship between the incidence of ROP and the influence of intrauterine environmental factors must be close. Using data on 1,887 premature infants, the mean and standard deviation of birthweight in each gestational weeks were calculated. Deviation of birthweight was considered to reflect the influence of intrauterine environmental factors and was evaluated by comparing the birthweight of a baby with the mean birthweight for the same number of gestational weeks. The incidence of ROP had no close relationship with the deviation of birthweight at each gestational age. Therefore, it was concluded that the influence of the modifying factors of birthweight had not any close relation with the incidence of ROP. At present we should use gestational age as the best scale to estimate infants' prematurity to predict ROP.
本研究是第二项利用1986 - 1987年两年间在爱知县获得的早产儿视网膜病变（ROP）流行病学调查数据的报告。为研究ROP，我们使用出生体重和胎龄来评估婴儿的早产情况。发现这两个参数与ROP的发病率密切相关。虽然胎龄接近胚胎年龄，但出生体重受宫内环境因素影响很大。为证实使用出生体重的重要性，ROP发病率与宫内环境因素影响之间的关系必须密切。利用1887名早产儿的数据，计算了每个孕周出生体重的均值和标准差。出生体重的偏差被认为反映了宫内环境因素的影响，并通过将婴儿的出生体重与相同孕周数的平均出生体重进行比较来评估。ROP的发病率与每个胎龄的出生体重偏差没有密切关系。因此，得出结论，出生体重修正因素的影响与ROP的发病率没有密切关系。目前，我们应使用胎龄作为评估婴儿早产情况以预测ROP的最佳指标。
