Berman J J, Moore G W, O'Neill T P, Liebelt A G, Saffiotti U
Department of Pathology, VA Medical Center, Baltimore, MD 21201.
Am J Pathol. 1993 Feb;142(2):351-2.
The National Cancer Institute established the Registry of Experimental Cancers in March 1970. This registry consists of a permanent collection of pathological materials on spontaneous and induced lesions in laboratory animals that includes histological slides, paraffin blocks, autopsy findings, pathological diagnoses, photographs, and experimental records. The material presently is composed of approximately 60,000 consecutive records and is a valuable resource for researchers interested in tumors and other lesions arising spontaneously or from specific induction protocols in experimental animals. The entire registry database was transferred to an object-oriented database that permits registry staff to write programs for the different data field objects, thus customizing searches and other database functions. Twenty-seven animal species are represented and a total of 6,496 diagnostic entities and 1,106 treatment and control protocols are listed. Archival material may be retrieved for analysis of molecular markers.
美国国立癌症研究所于1970年3月建立了实验性癌症登记处。该登记处长期收集实验动物自发和诱发损伤的病理材料，包括组织学切片、石蜡块、尸检结果、病理诊断、照片和实验记录。目前该材料由约60000份连续记录组成，对于对实验动物自发产生或特定诱导方案产生的肿瘤及其他损伤感兴趣的研究人员来说，是一份宝贵的资源。整个登记处数据库已转换为面向对象的数据库，这使得登记处工作人员能够为不同的数据字段对象编写程序，从而定制搜索及其他数据库功能。登记处涵盖了27种动物物种，共列出6496个诊断实体以及1106个治疗和对照方案。可以检索档案材料以分析分子标记。
