Furesz J
CMAJ. 1996 Nov 15;155(10):1423-6.
Of the 5551 confirmed measles cases reported in 1995 in the Americas, 2301 (41%) occurred in Canada. In this issue (see pages 1407 to 1413) Drs. Penny A. Sutcliffe and Elizabeth Rea describe a measles outbreak that occurred during that year in a highly vaccinated secondary school population in Toronto. Their findings support the use of a two-dose measles vaccination strategy. In this editorial the author explains how a two-dose strategy lowers the incidence of primary and secondary vaccine failures and thus reduces the number of susceptible people to below the outbreak threshold. Two-dose programs in Finland, Sweden and the United States have dramatically reduced the incidence rates of measles in those countries, and it is expected that the implementation of two-dose programs and "catch-up" campaigns in Canada and the remaining countries of the Americas will eliminate measles from the Western Hemisphere by the year 2000.
在1995年美洲地区报告的5551例确诊麻疹病例中,有2301例(41%)发生在加拿大。在本期杂志(见第1407至1413页)中,彭妮·A·萨克利夫博士和伊丽莎白·雷亚博士描述了当年在多伦多一所高度接种疫苗的中学人群中发生的麻疹疫情。他们的研究结果支持采用两剂次麻疹疫苗接种策略。在这篇社论中,作者解释了两剂次策略如何降低初次和再次疫苗接种失败的发生率,从而将易感人群数量减少到疫情爆发阈值以下。芬兰、瑞典和美国的两剂次接种计划已大幅降低了这些国家的麻疹发病率,预计在加拿大和美洲其他国家实施两剂次接种计划和“补种”活动将在2000年前使西半球消除麻疹。