耐万古霉素粪肠球菌V583的vanB基因在结构上与编码D-丙氨酸：D-丙氨酸连接酶以及糖肽抗性蛋白VanA和VanC的基因相关。
The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding D-Ala:D-Ala ligases and glycopeptide-resistance proteins VanA and VanC.
作者信息
Evers S, Sahm D F, Courvalin P
机构信息
Unité des Agents Antibactériens, Institut Pasteur, Paris, France.
出版信息
Gene. 1993 Feb 14;124(1):143-4. doi: 10.1016/0378-1119(93)90779-3.
PMID:8440477
Abstract
We report the cloning and sequencing of a 632-bp amplified fragment internal to the vanB gene of vancomycin-resistant (VmR) Enterococcus (En.) faecalis V583. The DNA fragment hybridized to VmR strains of En. faecium and En. faecalis, but not to their susceptible derivatives.
摘要
我们报告了耐万古霉素粪肠球菌V583的vanB基因内部一个632bp扩增片段的克隆和测序。该DNA片段与屎肠球菌和粪肠球菌的耐万古霉素菌株杂交，但不与其敏感衍生物杂交。
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