Mayberry J F, Newcombe R G, Rhodes J
Q J Med. 1980 Winter;49(193):63-8.
Two hundred and nineteen Cardiff residents were identified with Crohn's disease between 1934 and 1976, during which period 40 of them died. Young patients diagnosed under the age of 20 years had a significantly raised standardized mortality rate (SMR) which was 11. The risk of death was particularly high during the first two and a half years after diagnosis and again after the disease had been present for more than about 13 years. Case fatality has not diminished during the last 40 years despite changes in treatment.
1934年至1976年间，共确诊219名加的夫居民患有克罗恩病，其中40人死亡。20岁以下确诊的年轻患者标准化死亡率（SMR）显著升高，为11。确诊后的头两年半以及患病超过约13年后死亡风险尤其高。尽管治疗方法有所改变，但在过去40年里病死率并未降低。
