Cipolli M, Canciani M, Cavazzani M, Uras P, Zampieri P, Mastella G
Cystic Fibrosis Centre, Ospedale Civile Maggiore, Verona, Italy.
Eur J Pediatr. 1993 Mar;152(3):265-6. doi: 10.1007/BF01956160.
Although upper respiratory tract involvement is a common finding in cystic fibrosis (CF), there is no agreement on whether hearing is affected in these patients. We studied 75 CF subjects and 50 healthy age-matched children with the same audiological protocol. An original scoring system was used to quantify the degree of hearing involvement (normal, mild, moderate and severe) in each subject. Prevalence of ear involvement in children with CF was similar to that in age-matched control subjects (25.4% and 18% respectively, P > 0.05). Ear disease in CF was not related to pulmonary disease, radiological sinusitis, nasal polyposis, or use of parenteral aminoglycosides. These data showed that the risk of ear disease in CF was not increased even if patients with severe audiological involvement were described only in the CF group.
尽管上呼吸道受累是囊性纤维化（CF）的常见表现，但对于这些患者的听力是否受到影响尚无定论。我们采用相同的听力学方案对75名CF患者和50名年龄匹配的健康儿童进行了研究。使用一种原创的评分系统来量化每个受试者的听力受累程度（正常、轻度、中度和重度）。CF患儿的耳部受累患病率与年龄匹配的对照受试者相似（分别为25.4%和18%，P>0.05）。CF患者的耳部疾病与肺部疾病、放射性鼻窦炎、鼻息肉或肠外氨基糖苷类药物的使用无关。这些数据表明，即使仅在CF组中描述了听力严重受累的患者，CF患者患耳部疾病的风险也没有增加。
