吸烟与幽门螺杆菌感染
Cigarette smoking and Helicobacter pylori infection.
作者信息
Bateson M C
机构信息
General Hospital, Bishop Auckland, County Durham, UK.
出版信息
Postgrad Med J. 1993 Jan;69(807):41-4. doi: 10.1136/pgmj.69.807.41.
Abstract
The direct urease test was used in 462 patients with normal upper digestive tracts, 108 with duodenal ulcers and 43 with gastric ulcers who attended for upper digestive endoscopy in a prospective study. There was a strong association between Helicobacter pylori infection and current cigarette smoking in patients with normal endoscopy (49.6% vs 35.5%, P < 0.01). The associations of peptic ulcer both with H. pylori infection and cigarette smoking were also confirmed. The excess of peptic ulcer disease in cigarette smokers may be explained by their increased susceptibility to H. pylori infection.
摘要
在一项前瞻性研究中，对462例上消化道正常、108例十二指肠溃疡和43例胃溃疡且接受上消化道内镜检查的患者进行了直接尿素酶试验。内镜检查正常的患者中，幽门螺杆菌感染与当前吸烟之间存在密切关联（49.6%对35.5%，P<0.01）。消化性溃疡与幽门螺杆菌感染和吸烟之间的关联也得到了证实。吸烟者消化性溃疡疾病过多可能是因为他们对幽门螺杆菌感染的易感性增加。
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