Whishaw I Q, Tomie J A, Kolb B
Department of Psychology, University of Lethbridge, Alberta, Canada.
Behav Neurosci. 1992 Aug;106(4):597-603. doi: 10.1037//0735-7044.106.4.597.
Rats with aspirative lesions of the ventrolateral frontal cortex were tested on acquisition and postsurgical retention of an associative learning task that required that they learn a tactile-olfactory configural discrimination. The task required that they pull up a string to obtain attached food and that they identify the correct string using a compound of string size and odor. The rats were not impaired in initial learning or reversal of the olfactory elements of the discrimination. They were impaired in acquisition and retention of the compound, and their deficit was proportional to lesion size. The results confirm that the ventrolateral frontal cortex is involved in processing of olfactory information and imply that the prefrontal cortex is involved in at least certain types of cross-modal configural associative learning.
对腹外侧额叶皮质有吸入性损伤的大鼠进行了一项联想学习任务的习得和术后保持测试，该任务要求它们学习一种触觉 - 嗅觉构型辨别。任务要求它们拉起一根绳子以获取附着的食物，并使用绳子大小和气味的组合来识别正确的绳子。大鼠在辨别任务中嗅觉元素的初始学习或反转方面没有受损。它们在化合物的习得和保持方面受损，并且它们的缺陷与损伤大小成比例。结果证实腹外侧额叶皮质参与嗅觉信息的处理，并暗示前额叶皮质至少参与某些类型的跨模态构型联想学习。
