D'Agostini F, Izzotti A, De Flora S
Institute of Hygiene and Preventive Medicine, University of Genoa, Italy.
Mutagenesis. 1993 Jan;8(1):87-9. doi: 10.1093/mutage/8.1.87.
The light emitted by an uncovered tungsten halogen lamp (12 V, 50 W), equipped with a dichroic mirror, induced time-related and distance-related increases in the frequency of micronucleated lymphocytes following in vitro exposure. Peripheral blood lymphocytes from three healthy donors showed the same degree of sensitivity. This clastogenic effect could be ascribed to the emission of far-UV wavelengths (UVB and UVC) and was prevented by interposing a common glass cover. These results support the findings of our genotoxicity studies in repair-deficient bacteria and carcinogenicity studies in hairless mice, thereby suggesting possible health hazards associated with illumination with halogen quartz bulbs, to which an enormous number of individuals are nowadays exposed. These hazards can be simply avoided by using glass covers.
一个配有二向色镜的未加防护的卤钨灯（12伏，50瓦）发出的光，在体外照射后会导致微核淋巴细胞的频率随时间和距离增加。来自三名健康供体的外周血淋巴细胞表现出相同程度的敏感性。这种致断裂效应可归因于远紫外线波长（UVB和UVC）的发射，并且通过插入一个普通的玻璃罩可以防止。这些结果支持了我们在修复缺陷型细菌中的遗传毒性研究以及在无毛小鼠中的致癌性研究结果，从而表明与卤化石英灯泡照明相关的可能健康危害，如今大量个体都暴露于这种灯泡之下。通过使用玻璃罩可以简单地避免这些危害。
