一种与成熟B细胞慢性淋巴细胞增殖性疾病相关的新染色体异常：7号染色体长臂32区缺失（del(7)(q32)）
A new chromosomal anomaly associated with mature B-cell chronic lymphoproliferative disorders: del(7)(q32).
作者信息
Solé F, Woessner S, Florensa L, Montero S, Asensio A, Besses C, Sans-Sabrafen J
机构信息
Laboratori de Citologia Hematológica, Unitat d'Hematologia i Oncologia, Hospital Central L'Aliança, Barcelona, Spain.
出版信息
Cancer Genet Cytogenet. 1993 Feb;65(2):170-2. doi: 10.1016/0165-4608(93)90229-f.
PMID:8453604
Abstract
Among 63 patients with chronic lymphoproliferative disorders (CLPD) studied cytogenetically in our laboratory, four showed a del(7)(q32); in two it was the sole cytogenetic anomaly and in two it was part of a complex karyotype. We suggest that despite the rarity of this anomaly, it could be related to CLPD.
摘要
在我们实验室进行细胞遗传学研究的63例慢性淋巴细胞增殖性疾病（CLPD）患者中，有4例显示7号染色体长臂3区2带缺失（del(7)(q32)）；其中2例这是唯一的细胞遗传学异常，另外2例则是复杂核型的一部分。我们认为，尽管这种异常罕见，但可能与CLPD有关。
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