Urbain J L, Vekemans M C, Bouillon R, Van Cauteren J, Bex M, Mayeur S M, Van den Maegdenbergh V, Bataille G, Charkes N D, Malmud L S
Department of Nuclear Medicine, U.Z. Gasthuisberg, Leuven, Belgium.
J Nucl Med. 1993 Apr;34(4):576-81.
In this study, food distribution in the stomach and gastric antral motor activity in patients with longstanding diabetes have been evaluated. With use of a standard gastric emptying test with an acquisition protocol and a refined Fourier algorithm to analyze the data, antral contractions have been characterized and gastric motility parameters were correlated to gastric retention in 20 diabetic patients with or without gastroparesis and in 10 healthy subjects. The results of this study show that, in longstanding diabetes, gastric emptying retardation is accounted for by a retention of food in the proximal stomach, which is reflected by a prolonged lag phase as well as by a reduction in antral motor activity that is determined by a decrease in the amplitude of the antral contractions. This study demonstrates that scintigraphy can noninvasively characterize abnormalities of food distribution in the stomach and provides information similar to that obtained from manometry.
在本研究中，对长期糖尿病患者胃内食物分布及胃窦运动活性进行了评估。通过使用具有采集方案的标准胃排空试验及改进的傅里叶算法分析数据，对20例有或无胃轻瘫的糖尿病患者及10名健康受试者的胃窦收缩进行了特征描述，并将胃动力参数与胃潴留情况进行了关联分析。本研究结果表明，在长期糖尿病中，胃排空延迟是由于近端胃内食物潴留所致，这表现为延迟期延长以及胃窦运动活性降低，胃窦运动活性降低由胃窦收缩幅度减小所决定。本研究表明，闪烁扫描术可无创地描述胃内食物分布异常，并提供与测压法相似的信息。
