Bergan T, da Fonseca J
Department of Microbiology, University of Oslo, Norway.
Chemotherapy. 1993 Mar-Apr;39(2):96-104. doi: 10.1159/000239109.
The minimum inhibitory concentration of cefcanel, a new oral cephalosporin, has been determined for 182 clinical isolates, of which 84 were from the family Enterobacteriaceae, 45 were from the genus Streptococcus, 18 were nonfermentative rods, 25 were Haemophilus influenzae and 10 were Branhamella catarrhalis. In general, cefcanel was more active than the other cephalosporins against the species Escherichia coli, Klebsiella aerogenes and Proteus mirabilis. Among the genus Streptococcus only the enterococci were resistant to cefcanel. H. influenzae and B. catarrhalis showed also a reasonable susceptibility towards cefcanel. Oxidative rods were highly resistant to cefcanel.
已测定新型口服头孢菌素头孢卡奈对182株临床分离菌的最低抑菌浓度，其中84株来自肠杆菌科，45株来自链球菌属，18株为非发酵菌，25株为流感嗜血杆菌，10株为卡他莫拉菌。总体而言，头孢卡奈对大肠杆菌、产气克雷伯菌和奇异变形杆菌的抗菌活性高于其他头孢菌素。在链球菌属中，仅肠球菌对头孢卡奈耐药。流感嗜血杆菌和卡他莫拉菌对头孢卡奈也表现出一定的敏感性。氧化型杆菌对头孢卡奈高度耐药。
