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性信息素如何在浓度低于10⁻¹⁶ M时发挥作用。

How a sex pheromone might act at a concentration below 10(-16) M.

作者信息

Sumper M, Berg E, Wenzl S, Godl K

机构信息

Lehrstuhl Biochemie I, Universität Regensburg, Germany.

出版信息

EMBO J. 1993 Mar;12(3):831-6. doi: 10.1002/j.1460-2075.1993.tb05723.x.

DOI:10.1002/j.1460-2075.1993.tb05723.x
PMID:8458341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC413280/
Abstract

The sex-inducing pheromone of Volvox carteri is a glycoprotein that triggers development of males and females at a concentration below 10(-16) M. Evidence is presented for the existence of a novel mechanism of signal amplification operating within the extracellular matrix of this multicellular organism. A family of 70 kDa matrix glycoproteins denoted pherophorins bear a C-terminal domain being homologous to the sex-inducing pheromone. Under the influence of the pheromone, this domain is liberated by highly specific proteolysis.

摘要

团藻的性诱导信息素是一种糖蛋白，在浓度低于10^(-16) M时可触发雄性和雌性的发育。本文提供了证据，证明在这种多细胞生物的细胞外基质中存在一种新的信号放大机制。一类被称为信息素运载蛋白的70 kDa基质糖蛋白带有一个与性诱导信息素同源的C末端结构域。在信息素的影响下，该结构域通过高度特异性的蛋白水解作用被释放出来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/cb8e0945bd74/emboj00075-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/1f34e69c5122/emboj00075-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/5feac9df4e85/emboj00075-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/0b36815d0610/emboj00075-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/91321bd8927c/emboj00075-0038-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/908c0cbe151b/emboj00075-0038-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/cb8e0945bd74/emboj00075-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/1f34e69c5122/emboj00075-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/5feac9df4e85/emboj00075-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/0b36815d0610/emboj00075-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/91321bd8927c/emboj00075-0038-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/908c0cbe151b/emboj00075-0038-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef1/413280/cb8e0945bd74/emboj00075-0039-a.jpg

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本文引用的文献

1
The sexual inducer of Volvox carteri: purification, chemical characterization and identification of its gene.衣藻性引诱剂的分离、化学鉴定及其基因的鉴定。
EMBO J. 1987 Aug;6(8):2203-7. doi: 10.1002/j.1460-2075.1987.tb02491.x.
2
Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes.从十二烷基硫酸钠 - 聚丙烯酰胺凝胶中洗脱蛋白质、去除十二烷基硫酸钠以及酶活性的复性：大肠杆菌RNA聚合酶σ亚基、小麦胚芽DNA拓扑异构酶及其他酶的实验结果
Anal Biochem. 1980 Nov 15;109(1):76-86. doi: 10.1016/0003-2697(80)90013-5.
3
细胞类型特异性pherophorins 的揭示了细胞类型在细胞外基质生物合成中的相互作用。
Cells. 2022 Dec 29;12(1):134. doi: 10.3390/cells12010134.
4
How abiotic stress-induced socialization leads to the formation of massive aggregates in Chlamydomonas.生物胁迫诱导的团聚如何导致衣藻中大量聚集体的形成。
Plant Physiol. 2022 Oct 27;190(3):1927-1940. doi: 10.1093/plphys/kiac321.
5
Chlamydomonas CHT7 is involved in repressing DNA replication and mitotic genes during synchronous growth.衣藻CHT7在同步生长过程中参与抑制DNA复制和有丝分裂基因。
G3 (Bethesda). 2022 Mar 4;12(3). doi: 10.1093/g3journal/jkac023.
6
Whole transcriptome RNA-Seq analysis reveals extensive cell type-specific compartmentalization in Volvox carteri.全转录组 RNA-Seq 分析揭示了衣藻中广泛的细胞类型特异性区室化。
BMC Biol. 2017 Nov 28;15(1):111. doi: 10.1186/s12915-017-0450-y.
7
A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta.一种性诱导信息素会引发强壮半海链藻的细胞周期停滞并吸引配偶。
Sci Rep. 2016 Jan 20;6:19252. doi: 10.1038/srep19252.
8
Sex-inducing effect of a hydrophilic fraction on reproductive switching in the planarian Dugesia ryukyuensis (Seriata, Tricladida).亲水组分对琉球涡虫（Seriata，三肠目）生殖转换的诱导性影响
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Evolution of reproductive development in the volvocine algae.团藻目藻类生殖发育的演化
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Control of differentiation in Volvox.
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Symp Soc Dev Biol. 1970;29:59-100. doi: 10.1016/b978-0-12-395534-0.50009-1.
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5
Translational regulation of protein synthesis, in response to light, at a critical stage of Volvox development.在团藻发育的关键阶段，蛋白质合成的翻译调控对光作出响应。
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6
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J Cell Biol. 1989 Dec;109(6 Pt 2):3493-501. doi: 10.1083/jcb.109.6.3493.
10
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Proc Natl Acad Sci U S A. 1988 Dec;85(23):8998-9002. doi: 10.1073/pnas.85.23.8998.