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酿酒酵母一号染色体测序:LTE1基因与SPO7基因之间32 kb区域的分析。

Sequencing of chromosome I from Saccharomyces cerevisiae: analysis of a 32 kb region between the LTE1 and SPO7 genes.

作者信息

Ouellette B F, Clark M W, Keng T, Storms R K, Zhong W, Zeng B, Fortin N, Delaney S, Barton A, Kaback D B

机构信息

Biology Department, McGill University, Montréal, Que., Canada.

出版信息

Genome. 1993 Feb;36(1):32-42. doi: 10.1139/g93-005.

Abstract

The DNA sequencing and preliminary functional analysis of a 32 kb section of yeast chromosome I has been completed. This region lies on the left arm of the chromosome between the LTE1 and SPO7 genes and contains 14 open reading frames (ORFs) positioned closely together, with an average spacing of approximately 350 nucleotides between coding regions. Three of these ORFs correspond to previously identified genes, a further three show significant homology with other proteins, while the remaining eight ORFs share no significant homology to genes in the databases.

摘要

酵母一号染色体32 kb区段的DNA测序及初步功能分析已完成。该区域位于染色体左臂上LTE1和SPO7基因之间,包含14个紧密排列的开放阅读框(ORF),编码区域之间的平均间距约为350个核苷酸。其中三个ORF对应于先前鉴定的基因,另外三个与其他蛋白质具有显著同源性,而其余八个ORF与数据库中的基因没有显著同源性。

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