一种静纤毛顶端连接丝拉伸模型。
A model of stereociliary tip-link stretches.
作者信息
Geisler C D
机构信息
Department of Neurophysiology, University of Wisconsin-Madison 53706.
出版信息
Hear Res. 1993 Feb;65(1-2):79-82. doi: 10.1016/0378-5955(93)90203-d.
PMID:8458761
Abstract
A model of the tip-link stretches produced by angular deflections of the stereocilia of vertebrate acoustico-lateralis hair cells is presented. It is shown that tip-link stretch in the model is proportional to the angle of stereociliary deflection. By contrast, the stretch of a horizontal (e.g., row-to-row) link is proportional to the square of the angle of stereociliary deflection. Possible roles of these stretches in sensory transduction are discussed.
摘要
提出了一种由脊椎动物听觉侧线毛细胞静纤毛角向偏转产生的纤毛顶端连接拉伸模型。结果表明，模型中的纤毛顶端连接拉伸与静纤毛偏转角成正比。相比之下，水平（例如，排与排之间）连接的拉伸与静纤毛偏转角的平方成正比。讨论了这些拉伸在感觉转导中的可能作用。
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