Crepin O, Roussel-Delvallez M, Martin G R, Courcol R J
Bacteriology Laboratory, A. Calmette Hospital, Lille, France.
J Clin Microbiol. 1993 Mar;31(3):734-5. doi: 10.1128/jcm.31.3.734-735.1993.
The present study evaluates the effectiveness of BACTEC NR-26A resin-containing medium in removing eight antibiotics from blood cultures. Peak concentrations achievable clinically were chosen. All antibiotics were prepared in fresh human blood samples. Blood samples were obtained prior to and at 15 min and 2, 24, 48, and 72 h after inoculation. Aztreonam, ceftriaxone, imipenem, teicoplanin, and ticarcillin were partially removed from blood cultures.
本研究评估了含BACTEC NR - 26A树脂的培养基从血培养物中去除8种抗生素的效果。选择了临床上可达到的峰值浓度。所有抗生素均在新鲜人血样本中配制。在接种前、接种后15分钟以及2、24、48和72小时采集血样。氨曲南、头孢曲松、亚胺培南、替考拉宁和替卡西林从血培养物中被部分去除。