Dykens E M, Hodapp R M, Ort S I, Leckman J F
Yale University School of Medicine, New Haven, Connecticut.
J Autism Dev Disord. 1993 Mar;23(1):135-45. doi: 10.1007/BF01066423.
Adaptive behavior in males with fragile X syndrome was longitudinally examined in 17 subjects, ages 1 to 17. Subjects received adaptive behavior evaluations on two occasions within one of three age periods. All domains of the Vineland Adaptive Behavior Scales increased from youngest to oldest age groups, yet older subjects (ages 10 to 17) showed significant declines in their adaptive behavior scores from first to second testing. A relative strength in Daily Living Skills and weakness in Socialization emerged only among older subjects. There was a significant relationship between adaptive behavior and mental age scores in all subjects. Discussion emphasized the parallels between declines in IQ and adaptive behavior as well as the need for further research on adaptive skills in young adults with fragile X syndrome.
对17名年龄在1至17岁的脆性X综合征男性患者的适应性行为进行了纵向研究。研究对象在三个年龄阶段之一的时间内接受了两次适应性行为评估。文兰适应性行为量表的所有领域从最年轻年龄组到最年长年龄组均有所增加，但年长的研究对象（10至17岁）在第一次测试到第二次测试期间适应性行为得分显著下降。仅在年长的研究对象中出现了日常生活技能方面的相对优势和社交方面的劣势。所有研究对象的适应性行为与心理年龄得分之间存在显著关系。讨论强调了智商下降与适应性行为下降之间的相似之处，以及对脆性X综合征青年成人的适应技能进行进一步研究的必要性。
