Atiyeh B, Husmann D, Baum M
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9063.
Pediatrics. 1993 Apr;91(4):812-5.
The prevalence of contralateral renal abnormalities in noncystic-dysplastic kidney (NCDK) disease and renal agenesis is unknown. Twenty-four patients with NCDK disease and 16 patients with renal agenesis were studied in this 11-year retrospective study. In all patients the urinary system was evaluated by renal ultrasonography, and excretory urography or radionuclide scan. In addition, voiding cystourethrography was performed in 21 of 24 patients with NCDK disease and in 10 of 16 patients with renal agenesis. In those patients where voiding cystourethrography was performed, 14 (67%) patients with NCDK disease and 9 (90%) patients with renal agenesis had contralateral urologic abnormalities. Contralateral vesicoureteral reflux was the most common contralateral abnormality identified in 9 (43%) patients with NCDK disease and in 3 (30%) patients with renal agenesis. It is concluded that contralateral urologic abnormalities are common in patients with NCDK disease and in patients with renal agenesis and that vesicoureteral reflux is the most common contralateral abnormality noted.
非囊性发育异常性肾病(NCDK)和肾缺如患者中对侧肾脏异常的患病率尚不清楚。在这项为期11年的回顾性研究中,对24例NCDK疾病患者和16例肾缺如患者进行了研究。所有患者均通过肾脏超声、排泄性尿路造影或放射性核素扫描对泌尿系统进行评估。此外,24例NCDK疾病患者中的21例以及16例肾缺如患者中的10例进行了排尿性膀胱尿道造影。在进行排尿性膀胱尿道造影的患者中,14例(67%)NCDK疾病患者和9例(90%)肾缺如患者存在对侧泌尿系统异常。对侧膀胱输尿管反流是最常见的对侧异常,在9例(43%)NCDK疾病患者和3例(30%)肾缺如患者中被发现。研究得出结论,NCDK疾病患者和肾缺如患者中对侧泌尿系统异常很常见,且膀胱输尿管反流是最常见的对侧异常。