Imamura N, Nishijima M, Adachi K, Sano H
Shimizu Institute, Marine Biotechnology Institute Co., Ltd., Japan.
J Antibiot (Tokyo). 1993 Feb;46(2):241-6. doi: 10.7164/antibiotics.46.241.
Two novel antimycin antibiotics, urauchimycins A and B, were isolated from a fermentation broth of a Streptomyces sp. Ni-80. The strain was isolated from an unidentified sponge. Their chemical structures were determined by 2D NMR analysis. They are the first antimycin antibiotics which possess a branched side chain moiety. They exhibited inhibitory activity against morphological differentiation of Candida albicans.
从链霉菌属Ni-80的发酵液中分离出两种新型抗霉素抗生素，uroachimycins A和B。该菌株是从一种未鉴定的海绵中分离得到的。通过二维核磁共振分析确定了它们的化学结构。它们是首批具有支链侧链部分的抗霉素抗生素。它们对白色念珠菌的形态分化表现出抑制活性。
