Arthur K E, Perurena J
Servicio de Coloproctología, Hospital Metropolitano Amulfo Arias Madrid.
Rev Med Panama. 1993 Jan;18(1):1-15.
The author studied the medical records of 133 patients who underwent surgery for adenocarcinoma of the colon or rectum in the Metropolitan Hospital Complex Arnulfo Arias Madrid from June 1972 to July 1992. In 9 (6.7%) the tumor was staged as Dukes A, in 49 (36.8%) as Dukes B; in 60 (43.1%) as Dukes C and in 10 (16.7%) as Dukes D. The anatomical location of the tumor was the cecum in 9 (6.7%), the ascending colon in 3 (2.3%), the sigmoid colon in 44 (33%) and the rectum in 41 (31.6%). Of the rectal carcinomas 24 (58.5%) were in the inferior one third, 10 (24.3) were in the middle and 7 (17%) in the superior third. It is evident that nearly two thirds of the tumors were within reach of the digital rectal examination of the sigmoidoscopic examination. The parents ranged from 21 to 89 years of age and their median age was 63 years. 73 patients were women and 60 were men. 60.5% of the women and 39.5% of the men had carcinoma of the colon. The sexual prevalence of carcinoma of the rectum was different: 5% were in men and 43% were in women. 2.2% of the tumors were synchronous and 4% were metachronous. The author discusses the number, type and indications for the surgical procedures used. There were no perioperative deaths. The 5 year survival for adenocarcinomas of the colon was 100% for those patients with tumors staged as Dukes A, 78.5% for the Dukes B, 61.1% for the Dukes C and 0% for those staged as Dukes D. For the rectal adenocarcinomas the 5 year survival was 100% for those patients with tumors in Stage Dukes A, 57.1%, for those in Dukes B, 33.3 for those in Dukes C and 0% in those in Dukes D. These results indicate that these patients are seen in an advanced stage and point to the urgent need to make the diagnosis in early, curable stages. The low incidence of tumors in stage Dukes A indicates an indifference of the patients and/or the doctors to the symptoms and signs of this disease. The most frequent symptoms, in descending order were: bleeding on defecation (all types), change in bowel habits (diarrhea or constipation), abdominal pains, tenesmus and anemia (with its different clinical manifestations). Other symptoms were a palapable abdominal mass, feces with bloody mucus and rectal prolapse on defecation.(ABSTRACT TRUNCATED AT 400 WORDS)
作者研究了1972年6月至1992年7月在阿诺尔福·阿里亚斯·马德里大都会医院综合体接受结肠或直肠癌手术的133例患者的病历。其中9例(6.7%)肿瘤分期为杜克A期,49例(36.8%)为杜克B期;60例(43.1%)为杜克C期,10例(16.7%)为杜克D期。肿瘤的解剖位置为盲肠9例(6.7%),升结肠3例(2.3%),乙状结肠44例(33%),直肠41例(31.6%)。直肠癌中,24例(58.5%)位于下三分之一,10例(24.3%)位于中三分之一,7例(17%)位于上三分之一。显然,近三分之二的肿瘤可通过直肠指检或乙状结肠镜检查触及。患者年龄在21岁至89岁之间,中位年龄为63岁。73例为女性,60例为男性。60.5%的女性和39.5%的男性患有结肠癌。直肠癌的性别患病率不同:男性占5%,女性占43%。2.2%的肿瘤为同时性,4%为异时性。作者讨论了所采用手术程序的数量、类型和适应证。围手术期无死亡病例。结肠癌患者中,肿瘤分期为杜克A期的5年生存率为100%,杜克B期为78.5%,杜克C期为61.1%,杜克D期为0%。直肠癌患者中,肿瘤处于杜克A期的5年生存率为100%,杜克B期为57.1%,杜克C期为33.3%,杜克D期为0%。这些结果表明,这些患者就诊时已处于晚期,迫切需要在可治愈的早期阶段做出诊断。杜克A期肿瘤的低发病率表明患者和/或医生对该疾病的症状和体征漠不关心。最常见的症状,按出现频率递减依次为:排便时出血(各种类型)、排便习惯改变(腹泻或便秘)、腹痛、里急后重和贫血(伴有不同临床表现)。其他症状包括可触及的腹部肿块、带血性黏液的粪便和排便时直肠脱垂。(摘要截选至400字)