Sternad H, Albrecher B, Langsteger W, Eber O
Internen Abteilung, Krankenhauses der Barmherzigen Brüder Graz-Eggenberg.
Acta Med Austriaca. 1993;20(1-2):23-6.
Marked changes in plasma thyroid function parameters due to medication have been described in literature. We, therefore, studied the influence of routine administration of carbamazepine and diclofenac upon the radio T3/T4 distribution to specific thyroid transport proteins as well as their maximal binding capacity (MBC) for T4. Both drugs have been found to lead to changes in T3 and T4 distribution but not to any influence upon MBC. The parameters of thyroid function mostly revealed reduced FT3 and FT4 values while bTSH was affected only by carbamazepine administration.
文献中已描述了因药物治疗导致的血浆甲状腺功能参数的显著变化。因此，我们研究了卡马西平和双氯芬酸常规给药对放射性T3/T4在特定甲状腺转运蛋白上的分布及其对T4的最大结合能力（MBC）的影响。已发现这两种药物都会导致T3和T4分布的变化，但对MBC没有任何影响。甲状腺功能参数大多显示FT3和FT4值降低，而bTSH仅受卡马西平给药的影响。
